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Identifying other classes of drugs which could possess anti esophageal cancer properties is appealing. There is a growing body of literature that has shown the anti-cancer properties of statins in the setting of various malignancies. Herein, we summarize the current literature as it pertains to how the mevalonate pathway can be targeted by statins for potentially treating esophageal cancer. There is a growing body of literature that has shown the anti-cancer properties of statins in the setting of various malignancies. Herein, we summar