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ADHD Treatment Medication Adults with ADHD are usually treated with medication and psychosocial therapy. The medications used to treat ADHD include stimulants as well as non-stimulant medications. Stimulants, including lisdexamfetamine and methylphenidate, work on chemical messengers within the brain to boost mood and concentration, as well as control of impulses. Atomoxetine as well as guanfacine aren't stimulants ADHD drugs that are offered to adults, teenagers or children, if the