What Causes Trucking Accidents? Trucks make up a tiny portion of the vehicles on road however, they are extremely hazardous and cause serious injuries or even death. Accidents involving large vehicles can result when drivers are distracted or do not pay attention to their blind spots. Driver fatigue is also a factor in trucking accidents. Drivers work for long hours without taking breaks in order to fulfill their daily quotas. Driver Error Trucking accidents are caused by driver error which is a major problem. There are a myriad of factors th