https://www.selleckchem.com/pr....oducts/H-89-dihydroc
5 μM), ascorbate (200 μM), and N-acetylcysteine (500 μM) were further evaluated. p-CS triggered a striking increase in ROS production (+228%, p less then 0.01), in MDA content (+214%, p less then 0.005) and a decrease in glutathione (-47%, P less then 0.01). Pre-treatment of cells with probenecid, apocynin or antioxidants prevented the p-CS induced ROS production and oxidative insults. These results suggest that in uremic state, the intracellular accumulation of p-CS in adipose cells could contribute, through an activation
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