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5 (1.2-1.9); shoulder pain, 21% versus 9%, 2.6 (1.9-2.5); elbow pain, 14% versus 5%, 2.9 (2.0-4.2); wrist pain 14% versus 7%, 2.2 (1.5-3.1); and finger pain 13% versus 9%, 2.8 (2.0-3.9). Prevalence of musculoskeletal pain increased with age in controls but not in musicians. Professional orchestra musicians reported more pain in the back and upper extremity than other working people. Future research should focus on explaining differences in the occurrence of musculoskeletal disorders between musicians and the general population. Profession

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Recent advances in next-generation sequencing technologies have led to significant improvements in cancer genomic research and cancer treatment. Through the use of comprehensive cancer genome data, precision medicine has become more of a reality; albeit, at present, only ~10-15% of patients can benefit from current genomic testing practices. Improvements in cancer genome analyses have contributed to a better understanding of antitumor immunity and have provided solutions for targeting highly cancer-specific neoantigen