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Herein, we showed ATO cytotoxicity in pediatric SHH cell lines, with marked radiosensitizing effect for the MB-SHH TP53-mutated cells. These results highlight the potential of ATO, alone or in combination with radiotherapy, supporting further clinical investigations.Lineage-specific genetic programs rely on cell-restricted super-enhancers, which are platforms for high-density transcription factor occupation. It is not known whether super-enhancers synergize specifically with their native promoters or provide autonomous a

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Dates are a cherished fruit treasured for their natural sweet taste, nutritional benefits, and versatility. Amongst the myriad of date varieties offered, Kurma Ajwa sticks out as an one-of-a-kind and highly treasured selection. This day, known for its rich taste and social importance, provides distinctive top qualities that set it in addition to various other ranges. In this article, we'll