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Before new heart valves can be implanted safely in humans, animal experiments have to be performed. These animal experiments have to be clearly designed, analysed and reported to assess the accuracy and importance of the findings. We aimed to provide an overview of the reporting and methodological quality of preclinical heart valve research. We conducted a systematic literature search on biological and mechanical pulmonary valve implantations in large animals. We used the Animals in Research Reporting In Vivo Experiments (ARRIVE) guidel

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