https://www.selleckchem.com/pr....oducts/rg2833-rgfp10
Difficulty in cessation of drinking, smoking, or gambling has been widely recognized. Conventional theories proposed relative dominance of habitual over goal-directed control, but human studies have not convincingly supported them. Referring to the recently suggested "successor representation (SR)" of states that enables partially goal-directed control, we propose a dopamine-related mechanism that makes resistance to habitual reward-obtaining particularly difficult. We considered that long-standing behavior towards a certain rewa