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Therefore, when considering a sphenopalatine nerve block for treatment of headaches, both cluster and migraine, lidocaine should be the preferential treatment over intra-nasal cocaine.It has been well established and widely accepted that thrombolysis using recombinant tissue plasminogen activator (rTPA) is strongly beneficial for acute stroke patients. The sensitivity of brain tissue to ischemia causes this time dependence of the effectiveness of rTPA. Early recognition and management of a stroke is imperative for positive outcomes in su