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An early diagnosis and timely intervention may be the key measures to prevent the occurrence of fatal consequences caused by gas embolism. Spine surgeons should reconsider the pending results of using H2O2 during surgery. Prolonged prone positioning and semiclosed cavities may increase the risk of gas embolism. An early diagnosis and timely intervention may be the key measures to prevent the occurrence of fatal consequences caused by gas embolism. Percutaneous pedicle screws (PPS) are used to stabilize the spine after interbody fusi