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LC was attempted in 12 patients and conversion to open cholecystectomy was required in 3 (25%). Neither recurrence of cholecystitis nor late adverse event occurred during 6 months of follow-up in 10 patients who did not undergo cholecystectomy. CONCLUSIONS EUS-GBD with a combination of DPPS and NCT is considered an effective and safe technique both as BTS and palliation. This article is protected by copyright. All rights reserved.In this work, a comparison study on active sites (the total phenolic, total flavonoids, and total triterpe