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None of the clients had a prolonged QTc period just before the initiation of chloroquine therapy. CONCLUSIONS Chloroquine considerably prolongs the QTc interval in a clinically appropriate matter. This highlights the need for ECG monitoring when prescribing chloroquine to COVID-19 patients.Tumor necrosis element alpha (TNF) inhibitors have had a substantial impact in medicine considering that the approval associated with the very first drug of its class because of