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Health Issues That Affect German Shepherd Life Expectancy German Shepherds peak between the ages 2 and 6. They are at their best in terms of physical fitness and mental toughness. Their size makes them at a higher risk of developing cancer, muscle and joint issues, and other health issues that could have a negative impact on their lives. Working line German Shepherds typically lead more active lifestyles than show line counterparts. They require a diet high in nutrients to sustain their active lifestyles and exercise. Cushing's Disease German Shepherds are suscepti