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We conclude that social behavior deficits associated with the A350V Iqsec2 mutation may be rescued by enhancing AMPAR mediated synaptic transmission. The negative work climate influences the maladjustment of the staff and there are labor, physiological and psychological consequences in the workers. Work stress can appear as a result of the relationship between the individual, the work environment and the individual perception of threatening factors derived from work, which endangers physical, psychological and social well-being and incr