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Probes with favourable interplay energies are retained and clusters of those probes are ranked in accordance with their total interplay energies. It ought to be famous that there is no requirement that that is also the geometrically largest cluster. After CFG analysis has been carried out, the server generates a report detailing the outcomes of the prediction (Figure 1). This includes a listing of predicted practical websites, every consisting of a quantity of overlapping functional patches, delimited in house by spheres of various radii. For each predicted web

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4 [6.5, 14.3] ms for the 20 mg dose) as well as for the 7.5-mg dose of midazolam (8.2 [4.4, 12.1] ms). At 2 minutes after IV bolus, the upper bound of the 2-sided 90% confidence interval for ΔΔQTcI exceeded 10 ms only for the remimazolam 20-mg dose (6.3 [2.3, 10.2] ms). During the second study, during periods of stable heart rate, remimazolam had no clinically significant effect on QTc (peak ΔΔQTcI 3.4 [-1.1, 7.6] ms). CONCLUSION Remimazolam does not prolong cardiac repolarization (QTc). The methods reported here may allow assessment of