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ADHD Medications - Stimulant Or Non Stimulant? For many people stimulant medications are the first choice to treat ADHD. Some people have adverse reactions or they don't work. Some doctors prescribe stimulants in addition to non-stimulant ADHD medication. These include medications that treat high blood pressure like clonidine and guanfacine (Tenex). These are in addition to other medicines that help to increase awakening. Benefits Stimulants are the first medication doctors prescribe to treat ADHD. They help improve the c