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Best Medication For ADHD The majority of ADHD treatment plans contain medications. Finding the right dosage and medication can take some time. Be patient and openly communicate with your GP. increase the amount of the chemicals that regulate behavior in the brain. They come in short-acting and long-acting formulas. Short-acting medicines peak after a few hours and must be taken 2-3 times a day. Long-acting medicines last between 8 and 12 hours and are usually taken once a day. Stimulants Sti