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Right here we review the published researches dealing with the role of γδ T into the major autoimmune rheumatic conditions, including rheumatoid arthritis, juvenile idiopathic joint disease, ankylosing spondylitis, systemic lupus erythematosus and scleroderma, and animal models thereof. Due to their special properties spanning adaptive and innate resistant functions, the previously much deeper comprehension of this original T cell population