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Our results might offer a basis for establishing unique targets for OP treatment.Diagnosis of cerebrovascular illness (CVD) at early stages is really important for preventing sequential complications. CVD is normally involving abnormal cerebral microvasculature, which may affect cerebral-autoregulation (CA). A novel hybrid near-infrared diffuse optical tool and a finger plethysmograph were used to simultaneously detect low-frequency oscillations (LFOs) of