https://www.selleckchem.com/pr....oducts/pi3k-hdac-inh
Median time from CI therapy initiation was 40 months and from last dose was 28 months. Fatigue was reported by 28%, with higher fatigue scores in women than men; 12% reported difficulty sleeping. Aching joints (17%) and muscles (12%) were fairly common. Level of functioning was generally high. Overall QOL was excellent though 40% reported 'some or moderate' problems with anxiety/depression and 31% with pain/discomfort. CONCLUSIONS After CI therapy, long-surviving advanced melanoma patients commonly report fatigue but other
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