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The current status of the database, along with recent updates and improvements are described in this manuscript. In the absence of a safe, effective vaccine, the worldwide spread of COVID-19 (SARS-CoV-2) infection will continue. Laboratory tests with ideal precision, sensitivity, and specificity should be used in public health and clinical settings to gauge the extent of virus exposure. Toward this end, we evaluated the analytical and clinical performance of the Abbott SARS-CoV-2 IgG and the Roche Anti-SARS-CoV-2 immunoas

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© 2020 Wiley Periodicals, Inc.This article discloses a new horizon for the application of peroxides in medical chemistry. Stable cyclic peroxides demonstrated cytotoxic activity against cancer cells, besides a mechanism of cytotoxic action was proposed. Synthetic bridged 1,2,4,5-tetraoxanes and ozonides were effective against HepG2 cancer cells and some ozonides selectively targeted on liver cancer cells (SI for compounds 11b and 12a is 8 and 5 respectively). Tetraoxanes and ozonides in some cases were more specific than that of paclita