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Crucial conclusions are the following (1) numerous AQPs are expressed both in nasal mucosa and olfactory mucosa; (2) the appearance of AQPs within these areas is different in inflammatory diseases such as for instance AR or CRS, when compared with this in typical tissues; (3) the appearance of AQPs in CRS differs depending on the presence or absence of nasal polyps; and (4) the appearance of AQPs in areas related to olfaction differs from the others from that in the r

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