https://sodiumchannel-receptor.....com/index.php/the-e
We found that the peptide affinities of HLA alleles are not correlated with COVID-19 extent. The predicted bad binders for SARS-CoV-2 peptides belong to HLA-B subtypes that encode KIR ligands, including Bw4 and C1 (introduced by B*4601), which have a small F pocket and cannot accommodate SARS-CoV-2 CTL epitopes. Nonetheless, HLA-Bw4 poor binders were very theraputic for COVID-19 outcome, and individuals lacking the HLA-Bw4 motif had been at higher risk for serious infection from CO
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