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We highlight the role of the YAP/TAZ as mechanotransducers in stem cell self-renewal and differentiation in response to substrate stiffness, also the possibility of mechanobiology as the emerging field of regenerative medicines and three-dimensional tissue printing.Currently, the considerable decline in fossil fuel resources and the high rise in vehicle emissions have prompted researchers and governments to formulate strategies for sustainable energy development. In addition to imposing strict laws, promoting sustainable energy source

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