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Stimulant Vs Non Stimulant ADHD Medication The most frequently prescribed medication prescribed by healthcare professionals to treat ADHD is stimulants. They target specific chemicals in the brain, including dopamine and norepinephrine, to improve symptoms like the inability to focus and impulsivity. Nonstimulant drugs are an alternative treatment for those who aren't able to respond to stimulants. They also have less adverse effects. They target different neu