https://www.selleckchem.com/pr....oducts/Bafetinib.htm
SIGNIFICANCE This study demonstrates that integration of multi-omics data can help identify critical molecular determinants for effective targeted therapeutics.Expression of the transcription factor brachyury (TBXT) is normally restricted to the embryo, and its silencing is epigenetically regulated. TBXT promotes mesenchymal transition in a subset of common carcinomas, and in chordoma, a rare cancer showing notochordal differentiation, TBXT acts as a putative oncogene. We hypothesized that TBXT expression is controlled through epigene
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