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Results Twenty-seven participants completed the entire protocol and were included in the post-hoc analysis. Statistical analysis showed no interaction of group and time (p 0.05) on anxiety scores. Both groups improved depressive and executive functions over time, without time and group interaction (p s less then 0.05). No adverse effects were reported in either intervention group. Conclusion rTMS did not improve anxiety symptoms following high frequency rTMS in persons with moderate to severe TBI. Clinical Trial Registration www.Cl