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The pathophysiology of dystonia is defectively grasped. Instead of secondary types of dystonia, main dystonia has long been believed to lack any neuroanatomical substrate. During trajectory planning for DBS, nevertheless, conspicuous T2-hyperinstensive sign changes (SA) were subscribed within the target area, even in younger patients, where ischemia is rare. Fifty MRIs of major dystonia patients planned for DBS had been reviewed. Total basal ganglia (BG) volumes, also proportionate SA volumes, had been as
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