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The field of medical diagnostics has endeavored to explore single species of biomolecules for sensitive and informative disease diagnostic applications. Here, Raman hyperspectroscopy is used to analyze red blood cells for identifying Celiac disease (CD). CD is a common autoimmune disorder which affects approximately 1% of the population. The ingestion of gluten by an individual with CD will result in the body initiating a violent immune response which causes severe damage to the small intestine. If the disease goes undiagnosed