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79, 95% CI 1.08-2.97 for highest vs lowest quartile, P values for trend=0.045). Likewise, increasing changes in VAT area were independently associated with a higher risk of recurrent adenoma (HR 1.35, 95% CI 1.13-1.62 for change per 10cm increase; HR 1.62, 95% CI 1.04-2.52 for highest vs lowest quartile, P values for trend=0.001). Changes in subcutaneous adipose tissue area were not independently associated with CRA. Increasing changes in VAT area were longitudinally associated with a higher risk of incident and recurrent CRA, independent

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Staphylococcal enterotoxin-B (SE is one of the most potent bacterial superantigens that exerts profound toxic effects by inducing a cytokine storm. Inhaled SEB can cause acute respiratory distress syndrome (ARDS), which is often fatal and with no effective treatments. Efficacy of Δ -tetrahydrocannabinol (THC) was tested in a mouse model of SEB-mediated ARDS, in which lung inflammation, alterations in gut/lung microbiota and production of short-chain fatty acids (SCFAs) was measured. Gene dysregulation of lung epithelial