https://www.selleckchem.com/pr....oducts/favipiravir-t
RESULTS Fibrotic mouse livers showed enhanced [18F]-Alfatide uptake and retention compared to control livers. The radiotracer was demonstrated to bind specifically with integrin αvβ3 mainly expressed on aHSCs. Autoradiography and histopathology confirmed the PET imaging results. Further, the mRNA and protein level of integrin αvβ3 and its signaling complex were higher in CCl4 and BDL models compared to controls. Human fibrotic liver section results supported the animal findings. CONCLUSIONS Imaging hepatic integrin αvβ3 with P
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