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Freshwater consumption and wastewater discharge of economic activities have caused water scarcity problem in many regions. This study aims to develop a multi-dimensional diagnosis model (MDDM) to provide new insights for the sustainable development of regions which face water scarcity problem. In detail, the sectorial blue water, grey water and total water consumptions are assessed to reveal the direct effects of economic activities on water quantity and water quality. Then, hypothetical extraction method is integrated into input-output