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Based on the results, the levels of leached metal(loid)s from CBs in seawater peak soon after being released into the water, while for the freshwater, they occur after some days. This phenomenon could possibly have short-term and long-term effects on marine and freshwater organisms, respectively. Due to the ability of the dissolved PTEs to integrate into the aquatic/terrestrial food web and threaten human health, some control measures regarding the disposal of CBs are necessary.Accumulating evidence showed that berberine possessed the ant