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On the basis of our results, we assume that even in long-term rehabilitation of severely impaired non-fluent aphasia patients the applied treatment may support coactivation with dorsolateral prefrontal regions, suggested to be particularly involved in cognitive processing. This left-lateralized dorsolateral prefrontal-parietal network is supposed to be engaged in domain-general aspects of active phonological memory. To of our knowledge, no comparable studies are available as yet. Therefore, we hope that our study may serve to attract mo

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05); the expression of circSamd4a was significantly downregulated in the plasma of patients with VC (p0.01). The receiver operating characteristic (ROC) curves of circSamd4a in patients with VC and control group showed that the area under the curve (AUC) was 0.81 (95% CI 0.707-0.913; p0.001). CircSamd4a showed a stable downward trend in different specimens, and had significant advantages as a biomarker for diagnosis of VC. CircSamd4a showed a stable downward trend in different specimens, and had significant advantages as a biomarker for diag