https://www.selleckchem.com/pr....oducts/abbv-cls-484.
Primary sclerosing cholangitis (PSC), primary biliary cholangitis (PBC) and autoimmune hepatitis (AIH) are phenotypically distinct autoimmune liver diseases that progress to cirrhosis and liver failure; however, their histological fibrosis distribution differs. We investigated the extracellular matrix (ECM) profiles of patients with PSC, PBC, and AIH to establish whether the diseases display differential patterns of ECM turnover. Serum samples were retrospectively collected from the UK (test cohort; PSC n= 78; PBC n= 74; AIH n= 58)