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271 [95% CI 0.247-6.551], =0.775) or prosthesis thrombus (HR 0.50 [95% CI 0.070-3.548], =0.72). Kaplan-Meier analysis revealed similar overall survival in Group short and long (100 vs. 99 ± 1%, respectively; =0.25). Short-term (6 months) ATT after PFO closure did not impair the clinical outcome, with a preserved low rate of recurrent stroke (0.3% patient-year) and device thrombosis (0.2% patient-year) at 10-year follow-up. Short-term (6 months) ATT after PFO closure did not impair the clinical outcome, with a preserved low rate of recurren